How to Punctuate Conjunctive Adverbs (However, Therefore, Moreover)

Grammar rules

Words like "however," "therefore," "moreover," "furthermore," "consequently," and "nevertheless" are conjunctive adverbs — they connect two ideas the way a conjunction does, but they're grammatically adverbs, which means they follow different punctuation rules than "and," "but," or "so." Getting the punctuation wrong is extremely common because these words feel like conjunctions even though they don't behave like one.

At the start of a sentence: comma after

✓ However, the results were inconclusive.
✓ Therefore, we recommend a second trial.

Joining two complete sentences: semicolon before, comma after

This is the one people get wrong most often — using just a comma where a semicolon (or period) is required.

✗ The results were inconclusive, however, we recommend a second trial. (comma splice — see the comma splice page)
✓ The results were inconclusive; however, we recommend a second trial.

Because "however" isn't a true conjunction like "but," a comma alone can't join two complete sentences around it — you need a semicolon or a period, exactly as if "however" weren't there at all.

Mid-sentence, not joining two clauses: commas on both sides

✓ The results, however, were inconclusive.

Here "however" is inserted into a single sentence as a parenthetical aside rather than connecting two independent clauses, so it gets treated like any other interrupting phrase — commas on both sides.

Quick reference

Why this is worth getting right

The semicolon-vs-comma version of this mistake produces a comma splice, which is one of the more noticeable punctuation errors to an attentive reader — it's worth the extra beat of checking, especially in formal or professional writing where "however" and "therefore" show up constantly.

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